From novel insights of IMMUNOLOGY
Shaperon is a clinical stage biotech company developing Novel inflammasome inhibitors targeting immune-mediated inflammatory disorders with high unmet medical needs and Nanobody therapeutics
Inflammasomes are intracellular multiprotein complex in the innate immune system, the body’s first line of defense against PAMPs or host-derived cellular stress known as DAMPs. Once activated, inflammasomes produce highly proinflammatory cytokines and induce programmed cell death called pyroptosis. Dysregulation of inflammasomes is associated with a vast number of autoimmune and inflammatory disorders.
Nanobody is a single domain antibody that is the variable domain of heavy chain only antibody. It is naturally in the serum of camelidae (Camelid, Lama, Alpaca etc)
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